Helicobacter pylori infection with atrophic gastritis: An independent risk factor for colorectal adenomas

Table 2 Correlation between Helicobacter pylori infection and colorectal neoplasm

Parameter	HP (-), n = 3037	HP (+), n = 2981	OR (95%CI)	P value
Age in yr	48.130 (10.678)	48.040 (10.177)	0.999 (0.994-1.004)	0.745
Female	1026	1088	1
Male	2011	1893	0.888 (0.798-0.987)	0.027
Nonpolyp	2047	1936	1
Nonadenomatous polyp	514	509	1.047 (0.913-1.201)	0.512
Adenoma	476	536	1.191 (1.037-1.367)	0.013
Advanced adenoma	65	78	1.269 (0.908-1.774)	0.164
Villous adenoma	24	23	1.013 (0.570-1.801)	0.964
Size of adenoma ≥ 10 mm	49	64	1.381 (0.947-2.014)	0.093
High-grade dysplasia	5	8	1.692 (0.552-5.180)	0.357
Polyps number
One	509	521	1.082 (0.944-1.241)	0.258
Two or more	481	524	1.152 (1.003-1.323)	0.045
Polyps size
0-9 mm	925	963	1.101 (0.987-1.228)	0.086
≥ 10 mm	65	82	1.334 (0.958-1.858)	0.088

Correlation between Helicobacter pylori (+) and Helicobacter pylori (-) by logistic regression analysis. OR: Odds ratio; CI: Confidence interval; HP: Helicobacter pylori.