Helicobacter pylori infection with atrophic gastritis: An independent risk factor for colorectal adenomas

Table 1 Baseline characteristics of 6018 subjects

Parameter	Nonpolyp, n = 3983	Adenoma, n = 1012	Nonadenomatous polyp, n = 1023	Advanced adenoma, n = 143	aP value	bP value	cP value
Male/female	2336/1647	780/232	788/235	110/33	< 0.001	< 0.001	< 0.001
HP (+/-)	1936/2047	536/476	509/514	78/65	0.013	0.512	0.165
AG (+/-)	347/3636	139/873	116/907	21/122	< 0.001	0.016	0.049
Smoker (+/-)	1029/2954	402/610	430/593	61/82	< 0.001	< 0.001	< 0.001
Alcohol (+/-)	1423/2560	494/518	476/547	68/75	< 0.001	< 0.001	0.006
Age in yr	46.430 (10.150)	52.680 (9.981)	50.010 (10.269)	53.310 (9.738)	< 0.001	< 0.001	< 0.001
BMI	23.611 (3.160)	24.355 (2.938)	24.667 (3.099)	24.809 (2.929)	< 0.001	< 0.001	< 0.001
SBP	123.950 (17.747)	129.700 (18.488)	127.810 (18.388)	131.650 (17.271)	< 0.001	< 0.001	< 0.001
DBP	73.410 (12.255)	76.990 (12.036)	75.910 (12.541)	77.520 (11.798)	< 0.001	< 0.001	< 0.001
TC	5.296 (1.076)	5.434 (1.155)	5.387 (1.077)	5.528 (1.083)	< 0.001	0.016	0.012
TG	1.771 (1.586)	1.982 (1.784)	2.001 (1.525)	2.194 (1.693)	< 0.001	< 0.001	0.002
HDL	1.296 (0.330)	1.252 (0.330)	1.216 (0.304)	1.237 (0.335)	< 0.001	< 0.001	0.034
LDL	3.169 (0.841)	3.253 (0.866)	3.258 (0.855)	3.259 (0.905)	0.005	0.003	0.208
FBG	4.818 (1.136)	5.065 (1.422)	5.055 (1.395)	5.091 (1.608)	< 0.001	< 0.001	0.047

^aTwo-sided P values for the difference between adenoma and nonpolyp were based on the χ² test and t test.

^bTwo-sided P values for the difference between nonadenomatous polyp and nonpolyp were based on the χ² test and t test.

^cTwo-sided P values for the difference between advanced adenoma and nonpolyp were based on the χ² test and t test. HP: Helicobacter pylori; AG: Atrophic gastritis; BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; TC: Total cholesterol; TG: Triglyceride; HDL: High-density lipoprotein; LDL: Low-density lipoprotein; FBG: Fasting blood glucose.