Resveratrol alleviates intestinal mucosal barrier dysfunction in dextran sulfate sodium-induced colitis mice by enhancing autophagy

Figure 2 Clinical evaluation of dextran sulfate sodium-induced chronic colitis by disease activity index, body mass loss and colon length (n = 12 for the control group, n = 9 for disease activity index group, n = 11 for dextran sulfate sodium + 5-aminosalicylic acid group, n = 12 for dextran sulfate sodium + resveratrol treatment group). A: The disease activity index score was reduced in the resveratrol treated group compared with the dextran sulfate sodium group (^aP < 0.05); B and C: Resveratrol treatment increased the body mass and colon length of dextran sulfate sodium-induced colitis mice. Body mass loss was calculated as (detected body mass - initial mass)/initial mass. DSS: Dextran sulfate sodium; 5-ASA: 5-aminosalicylic acid; RES: Resveratrol.