Acute liver failure and death predictors in patients with dengue-induced severe hepatitis

Table 4 Summary of the clinical characteristics of dengue-induced severe hepatitis patients with acute liver failure

Number	Sex	Age	Dengue severity	Dengue complications					Treatment for ALF/HE	Duration (d)			Treatment outcome
				Sepsis	ARDS	Syst. Bleed.	Renal failure	Other		HE	ICU	Hospital	Status	Cause of death
1	F	23	DSS	No	No	Yes	Yes	No	None	1	1	3	Dead	CV failure
2	F	19	DSS	No	No	Yes	Yes	No	NAC	2	2	4	Dead	CV failure
3	M	11	DSS	Yes	No	Yes	Yes	No	None	5	21	22	Dead	Liver failure
4	M	16	DSS	No	No	Yes	Yes	DIC	SPAD NAC	4	7	26	Cured	-
5	F	21	DSS	No	Yes	Yes	Yes	DIC	Mannitol steroids	5	7	8	Dead	Bleeding complication
6	F	54	DSS	No	No	Yes	Yes	No	None	6	-	106	Cured	-
7	F	35	DSS	No	No	Yes	Yes	SICM	None	2	2	4	Dead	CV failure
8	M	16	DSS	No	No	No	No	No	None	3	3	8	Cured	-
9	M	24	DHF	Yes	Yes	Yes	Yes	DIC, HLH	NAC	10	37	78	Cured	-
10	F	17	DHF	No	No	Yes	Yes	No	SPAD NAC	4	4	11	Cured	-
11	M	18	DHF	Yes	No	Yes	Yes	DIC	NAC	10	33	40	Dead	Bleeding complication
12	M	33	DHF	Yes	No	Yes	Yes	DIC, ANP	MARS NAC	4	58	63	Dead	Uncontrolled sepsis
13	M	52	DSS	No	No	No	Yes	ANP	None	2	2	2	Dead	CV failure
14	F	14	DHF	No	No	No	Yes	No	3% NaCl	2	7	7	Cured	-
15	M	11	DSS	No	Yes	Yes	Yes	DIC	SPAD	6	6	6	Dead	CV failure
16	M	39	DHF	No	No	Yes	No	No	NAC	5	8	16	Cured	-
17	M	13	DSS	Yes	Yes	Yes	Yes	No	None	5	5	5	Dead	CV failure

F: Female; M: Male; Syst. Bleed.: Systemic bleeding; HE: Hepatic encephalopathy; ALF: Acute liver failure; CLS: Capillary leakage syndrome; ARDS: Acute respiratory distress syndrome; DHF: Dengue hemorrhagic fever; DSS: Dengue shock syndrome; WI: Within; DIC: Disseminated intravascular coagulation; CV: Cardiovascular; SICM: Stress-induced cardiomyopathy; HLH: Hemophagocytic lymphangiohistiocytosis; ANP: Acute necrotizing pancreatitis; NAC: N-acetylcysteine; SPAD: Single-pass albumin dialysis; MARS: Molecular adsorbent recirculating system.