Bowel function and quality of life after minimally invasive colectomy with D3 lymphadenectomy for right-sided colon adenocarcinoma

Table 2 Assessment of quality of life, function, and symptoms

	Preoperative (n = 57)	3 mo (n = 47)	6 mo (n = 52)	12 mo (n = 52)	18 mo (n = 25)	P value1	P value2
Global health status/QOL
Global health status/QOL	59.5	72.2	73.4	74.0	74.0	0.001	0.145
Functional scales
Physical functioning	87.4	87.8	86.4	90.0	88.3	0.530	0.591
Role functioning	86.8	87.9	91.7	96.5	98.7	0.001	0.716
Emotional functioning	81.9	90.6	94.4	97.1	99.3	< 0.001	0.795
Cognitive functioning	91.2	92.2	93.3	95.5	94.0	0.104	0.291
Social functioning	81.6	87.6	91.0	96.5	97.3	< 0.001	0.135
Sum	428.9	446.1	456.8	475.6	477.6	< 0.001	0.568
Symptom scales/items
Fatigue	22.4	21.3	16.9	10.9	12.0	0.001	0.207
Nausea and vomiting	8.8	2.1	2.6	2.2	0.0	0.001	0.470
Pain	17.8	8.5	7.1	1.6	2.0	< 0.001	0.278
Dyspnea	9.9	6.4	10.9	3.8	1.3	0.021	0.059
Insomnia	14.6	17.0	12.8	6.4	4.0	0.009	0.005
Appetite loss	18.7	9.2	10.3	1.3	1.3	< 0.001	0.285
Constipation	18.1	7.1	10.3	5.8	5.3	0.006	0.066
Diarrhea	15.8	12.8	12.2	7.1	5.3	0.010	0.909
Financial difficulties	21.1	14.2	16.0	5.8	9.3	< 0.001	0.115
Sum	147.3	98.6	98.9	44.9	40.7	< 0.001	0.017
Chemotherapy	0	18 (38.3)	18 (34.6)	1 (1.9)	0	NA	NA
FOLFOX	0	17 (36.2)	17 (32.7)	1 (1.9)	0	NA	NA
FL	0	1 (2.1)	1 (1.9)	0	0	NA	NA

¹P values correspond to the changes in values over the period.

²P values correspond to the correlation between scales and chemotherapy. Values are presented as mean (range) or n (%). FOLFOX: Oxaliplatin-based chemotherapy regimen; FL: 5-fluorouracil with leucovorin regime; QOL: Quality of life; NA: Not available.