Current status of Helicobacter pylori eradication and risk factors for eradication failure

Table 3 Subgroup comparison of eradication rates

	Antibiotic regimen	Successful eradication (n)	Total (n)	Eradication rate (%)	95%CI (%)
Primary	Total	1751	2237	78.3	76.6-80.0
	Amoxicillin plus clarithromycin	980	1166	84.0	81.9-86.1
	Amoxicillin plus levofloxacin	47	54	87.0	78.1-96.0
	Amoxicillin plus furazolidone	8	11	72.7	46.4-99.0
	Clarithromycin plus metronidazole	61	112	54.5	45.2-63.7
	Clarithromycin plus levofloxacin	647	871	74.3	71.4-77.2
	Clarithromycin plus furazolidone	7	20	35.0	14.1-55.9
	Levofloxacin plus furazolidone	1	3	33.3	0.0-86.7
Rescue	Total	248	373	66.5	61.7-71.3
	Amoxicillin plus clarithromycin	81	105	77.1	69.1-85.2
	Amoxicillin plus levofloxacin	13	22	59.1	38.5-79.6
	Amoxicillin plus furazolidone	42	52	80.8	70.1-91.5
	Clarithromycin plus metronidazole	20	36	55.6	39.3-71.8
	Clarithromycin plus levofloxacin	73	128	57.0	48.5-65.6
	Clarithromycin plus furazolidone	8	14	57.1	31.2-83.1
	Levofloxacin plus furazolidone	11	16	68.8	46.0-91.5

The following antibiotic dosages were prescribed: Amoxicillin, 1000 mg bid; clarithromycin, 500 mg bid; levoflaxacin, 500 mg qd or 200 mg bid; furazolidone, 100 mg bid; metronidazole, 200 mg bid, 400 mg bid, or 200 mg tid.