Association between human leukocyte antigen gene polymorphisms and multiple EPIYA-C repeats in gastrointestinal disorders

doi:10.3748/wjg.v26.i32.4817

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Aug 28, 2020 (publication date) through Nov 7, 2024

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Aug 28, 2020; 26(32): 4817-4832
Published online Aug 28, 2020. doi: 10.3748/wjg.v26.i32.4817

Table 4 The comparison of human leukocyte antigen alleles which increase or decrease the duodenal ulcer risk in duodenal ulcer subgroup in terms of CagA+(≥ 2) EPIYA-C, n (%)

	DU (≥ 2) EPIYA-C (n = 14, alleles = 28)	DU (< 2) EPIYA-C (n = 36, alleles = 72)	OR^c	95%CI			P value
	DU (≥ 2) EPIYA-C (n = 14, alleles = 28)	DU (< 2) EPIYA-C (n = 36, alleles = 72)	OR^c	Minimum	Maximum		P value
HLA-A*02	10 (36)	20 (27)	1.44	0.53		3.62	0.4380
HLA-B*35	4 (14)	14 (19)	0.80	0.24		0.680	0.0201
HLA-DRB1*13	6 (21)	6 (8)	3	0.87		10.26	0.0801
HLA-DQA1*01	10 (36)	26 (36)	0.9	0.39		2.44	0.9704
HLA-DQB1*06	8 (28)	16 (22)	1.4	0.52		3.75	0.5340

HLA: Human leukocyte antigen; DU: Duodenal ulcer; CI: Confidence interval; OR: Odds ratio.

Citation: Saribas S, Demiryas S, Yilmaz E, Uysal O, Kepil N, Demirci M, Caliskan R, Dinc HO, Akkus S, Gareayaghi N, Kirmusaoglu S, Ozbey D, Tokman HB, Koksal SS, Tasci I, Kocazeybek B. Association between human leukocyte antigen gene polymorphisms and multiple EPIYA-C repeats in gastrointestinal disorders. World J Gastroenterol 2020; 26(32): 4817-4832
URL: https://www.wjgnet.com/1007-9327/full/v26/i32/4817.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i32.4817