Monocyte-to-lymphocyte ratio as a prognostic factor in peripheral whole blood samples of colorectal cancer patients

Table 2 Correlations between neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio status and platelet and neutrophil-to-lymphocyte ratio status in pre and postoperative whole blood samples and clinicopathological features of patients with colorectal cancer

Parameter		n	NLR-PLR status		PLT-NLR status
		160	Pre- P value	Post- P value	Pre- P value	Post- P value
Age (yr)	< 60	40	0.326	0.120	0.427	0.155
	> 60	120
Sex	Female	64	0.729	0.370	0.258	0.435
	Male	96
Location	Right-side	20	0.963	0.167	0.475	0.183
	Transverse	14
	Left-side	15
	Sigmoid	29
	Rectum	82
Tumour growth	Expanding	133	0.671	0.776	0.349	0.728
	Infiltrate	27
Tumour size	< 2.5 cm	27	0.359	0.401	0.015a	0.554
	2.5-5.0 cm	106
	> 5.0 cm	27
Histological type	Mucinous	30	0.226	0.002a	0.895	0.002a
	Adenocarcinoma	130
Percentage of mucinous component	10%-30%	15	0.730	0.009a	0.810	0.007a
	30%-50%	15
TNM stage	1	42	0.722	0.583	0.266	0.703
	2	31
	3	69
	4	18
Grade of malignancy	2	148	0.687	0.883	0.464	0.864
	3	12
pT stage	1	3	0.590	0.196	0.853	0.253
	2	62
	3	91
	4	4
Venous invasion	Absent	113	0.437	0.993	0.618	0.917
	Present	46
Lymphatic invasion	Absent	121	0.917	0.994	0.414	0.940
	Present	38
Perineural invasion	Absent	143	0.714	0.343	0.037a	0.368
	Present	17
Lymph node metastasis	Absent	81	0.292	0.913	0.070	0.995
	Present	79
Distant metastasis	Absent	143	0.152	0.354	0.157	0.378
	Present	17
Tumour deposits	Absent	133	0.910	0.320	0.670	0.293
	Present	27
Tumour budding	Absent	94	0.771	0.575	0.302	0.692
	Present	66
Necrosis	Absent	45	0.599	0.521	0.273	0.449
	Focal	61
	Moderate	36
	Extensive	18
Fibrosis	Absent	11	0.258	0.390	0.400	0.282
	Focal	72
	Moderate	43
	Extensive	34

^aP < 0.05. TNM stage: Tumour-Node-Metastasis; PLT-NLR status: Platelet and neutrophil-to-lymphocyte ratio; NLR-PLR status: Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio; Pre: Preoperative blood samples; Post: Postoperative blood samples.