Establishment of a pattern recognition metabolomics model for the diagnosis of hepatocellular carcinoma

Table 1 General characteristics of patients and healthy controls

Characteristics		C (n = 30)	Y (n = 29)	N (n = 31)	P value
Sex (Male/Female)		25/5	21/8	25/6	0.565
Age (yr)		52.93 ± 11.01	56.63 ± 9.15	51.23 ± 11.79	0.148
Pathogens	HBV	25	24	/	0.720
	HCV	1	2
	HBV + HCV	1	0
	None	3	3
AFP (ng/mL)	> 200	11	0	/	0.000
	50-199	4	1
	< 50	15	28
ALT (U/L)		162.32 ± 201.06	91.02 ± 156.39	20.34 ± 8.43	0.000
AST (U/L)		146.35 ± 112.70	114.49 ± 191.67	21.59 ± 4.51	0.012
TBIL (μmol/L)		39.21 ± 68.38	40.87 ± 42.41	9.66 ± 2.66	0.015
DBIL (μmol/L)		17.91 ± 34.43	17.90 ± 23.03	4.49 ± 1.38	0.044
TP (g/L)		62.42 ± 10.95	74.14 ± 8.05	72.31 ± 3.96	0.000
ALB (g/L)		33.51 ± 6.30	37.65 ± 7.64	45.36 ± 2.62	0.000
Child-Pugh score (A/B)		18/12	15/14	/	0.353

AFP: α-fetoprotein; ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; DBIL: Direct bilirubin; TBIL: Total bilirubin; TP: Total protein.