Clinical Trials Study
Copyright ©The Author(s) 2020.
World J Gastroenterol. Aug 14, 2020; 26(30): 4501-4522
Published online Aug 14, 2020. doi: 10.3748/wjg.v26.i30.4501
Table 5 Virologic response and change in serum hepatitis B virus DNA level after treatment
Treatment responseTreatment (ICE) group (n = 199)Control group ( n = 196)χ2/ZP value
48 wk
Patients with HBV DNA level decline > 2 log10 IU/mL, n (%)30 (15.08)13 (6.63)7.2550.007
Patients with HBV DNA level ≤ 4 log10 IU/mL, n (%)20 (10.05)5 (2.55)9.3670.002
Patients with undetectable HBV DNA (≤ 20 IU/mL), n (%)2 (1.01)0 (0.00)1.9800.159
96 wk
Patients with HBV DNA level decline > 2 log10 IU/mL, n (%)60 (30.15)12 (6.12)38.2490.000
Patients with HBV DNA level ≤ 4 log10 IU/mL, n (%)37 (18.59)6 (3.06)24.5550.000
Patients with undetectable HBV DNA (≤ 20 IU/mL), n (%)4 (2.01)0 (0.00)2.2270.136

  • Citation: Xing YF, Wei CS, Zhou TR, Huang DP, Zhong WC, Chen B, Jin H, Hu XY, Yang ZY, He Q, Jiang KP, Jiang JM, Hu ZB, Deng X, Yang F, Li FY, Zhao G, Wang LC, Mi YQ, Gong ZJ, Guo P, Wu JH, Shi WQ, Yang HZ, Zhou DQ, Tong GD. Efficacy of a Chinese herbal formula on hepatitis B e antigen-positive chronic hepatitis B patients. World J Gastroenterol 2020; 26(30): 4501-4522
  • URL: https://www.wjgnet.com/1007-9327/full/v26/i30/4501.htm
  • DOI: https://dx.doi.org/10.3748/wjg.v26.i30.4501