Gadoxetic acid magnetic-enhanced resonance imaging in the diagnosis of cholangiocarcinoma

Figure 2 Mass forming cholangiocarcinoma. On a background of the alcohol-related cirrhotic liver, there is a 2 cm lesion in segment VIII with capsular retraction (white arrow). The lesion is hypointense on T1 IP and OP images. A and B: Slightly hyperintense on T2 and SPAIR; C and D: DWI restriction; E: The dynamic enhancement pattern after gadoxetic acid administration is a peripheral rim of enhancement in arterial and portal phase; G and H: Progressive centripetal enhancement on the delayed phase; I: The lesion demonstrates hypointensity in the hepatobiliary phase; L: The patient underwent percutaneous liver biopsy. Biopsy specimen stained with hematoxylin and eosin respectively at 4 × and 20 ×; M and N: Showed an adenocarcinoma (orange arrow) on a background of the cirrhotic liver (orange arrow); N: The magnification better depicts the appearance of the adenocarcinoma with the tubular aspect. The immunohistochemistry confirmed the positivity for PDX1 and CK7 and negativity for CDX2 and CK20, in keeping with cholangiocarcinoma.