Detection of reflux-symptom association in children with esophageal atresia by video-pH-impedance study

doi:10.3748/wjg.v26.i28.4159

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 28, 2020; 26(28): 4159-4169
Published online Jul 28, 2020. doi: 10.3748/wjg.v26.i28.4159

Table 1 Symptoms and signs that may be associated with gastroesophageal reflux in infants and children[9]

Symptoms	Signs
General	General
Discomfort/irritability¹	Dental erosion
Failure to thrive	Anemia
Feeding refusal
Dystonic neck posturing (Sandifer syndrome)
Gastrointestinal	Gastrointestinal
Recurrent regurgitation with/without	Esophagitis
vomiting in the older children	Esophageal stricture
Heartburn/chest pain²	Barrett esophagus
Epigastric pain²
Hematemesis
Dysphagia/odynophagia
Airway	Airway
Wheezing	Apnea spells
Stridor	Asthma
Cough	Recurrent pneumonia associated with aspiration
Hoarseness	Recurrent otitis media

¹If excessive irritability and pain is the single manifestation, it is unlikely to be related to gastroesophageal reflux disease.

²Typical symptoms of gastroesophageal reflux disease in older children.

Citation: Maholarnkij S, Sanpavat A, Decharun K, Dumrisilp T, Tubjareon C, Kanghom B, Patcharatrakul T, Chaijitraruch N, Chongsrisawat V, Sintusek P. Detection of reflux-symptom association in children with esophageal atresia by video-pH-impedance study. World J Gastroenterol 2020; 26(28): 4159-4169
URL: https://www.wjgnet.com/1007-9327/full/v26/i28/4159.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i28.4159