Helicobacter pylori-induced inflammation masks the underlying presence of low-grade dysplasia on gastric lesions

Table 4 Probability of detecting low-grade dysplasia randomly or on visible lesions after Helicobacter pylori eradication

	Univariate		Multivariate
Variable	OR (95% CI)	P value	OR1 (95%CI)	P value
Age, yr	1.05 (1.01-1.11)	< 0.02	1.05 (1.00-1.10)	0.07
Gender
Female	1.002		-
Male	1.73 (0.69-4.37)	0.24	-	-
BMI, kg/m2	0.93 (0.75-1.15)	0.49	-	-
Alcohol use
No	1.002		1.002
Yes	4.33 (1.63-11.51)	< 0.01	3.88 (1.31-11.49)	0.01
Drug use
No	1.002		-
Yes	1.45 (0.54-3.94)	0.46	-	-
MALT hyperplasia regression/reduction
No	1.002		-
Yes	3.90 (1.20-7.91)	< 0.02	3.10 (1.05-9.12)	0.04
APCA and/or AIF antibody positivity
No	1.002
Yes	5.30 (1.44-19.56)	0.01	5.47 (1.33-22.39)	< 0.02

¹Ajusted for age, alcohol use, Mucosa-associated lymphoid tissue hyperplasia reduction/regression and anti-parietal cell antibody and/or anti-intrinsic factor antibody positivity.

²Reference group. LGD: Low-grade dysplasia; H. pylori: Helicobacter pylori; OR: Odds ratio; BMI: Body mass index; MALT: Mucosa-associated lymphoid tissue; APCA: Anti-parietal cell antibody; AIF: Anti-intrinsic factor.