Copyright
©The Author(s) 2020.
World J Gastroenterol. Jul 14, 2020; 26(26): 3780-3791
Published online Jul 14, 2020. doi: 10.3748/wjg.v26.i26.3780
Published online Jul 14, 2020. doi: 10.3748/wjg.v26.i26.3780
Table 5 Sensitivity, specificity, positive and negative predictive value of recalculated cutoff values of anti-tissue transglutaminase antibodies and anti-deamidated gliadin peptide antibodies autoantibodies titers and their combination with small bowel ultrasonography for prediction of villous atrophy in patients with celiac disease
| Characteristics | Sensitivity (%) (95%CI) | Specificity (%) (95%CI) | Accuracy (%) (95%CI) | Positive predictive value (%) (95%CI) | Negative predictive value (%) (95%CI) |
| Autoantibodies aTTG IgA (cutoff: 13.4) | 66.7 (41.0-86.7) | 93.7 (84.5-98.2) | 87.7 (78.5-93.9) | 75.0 (52.4-89.1) | 90.8 (83.6-95.0) |
| Autoantibodies aTTG IgG (cutoff: 6.7) | 33.3 (13.3-59.0) | 87.3 (76.5-94.4) | 75.3 (64.5-84.2) | 42.9 (23.0-65.3) | 82.1 (76.5-86.6) |
| Autoantibodies aDGP IgA (cutoff: 22.6) | 72.2 (46.5-90.3) | 90.0 (79.5-96.2) | 85.9 (76.2-92.7) | 68.4 (49.1-83.0) | 91.5 (83.6-95.8) |
| Autoantibodies aDGP IgG (cutoff: 28.8) | 61.1 (35.8-82.7) | 90.0 (79.5-96.2) | 83.3 (73.2-90.8) | 64.7 (44.1-81.0) | 88.5 (81.1-93.3) |
| Autoantibodies aTTG IgA (cutoff 13.4) AND ultrasonography | 47.1 (23.0-72.2) | 98.0 (89.2-99.9) | 84.9 (73.9-92.5) | 88.9 (51.9-98.3) | 84.2 (77.3-89.3) |
| Autoantibodies aDGP IgA (cutoff 22.6) AND ultrasonography | 52.9 (27.8-77.0) | 97.8 (88.5-99.9) | 85.7 (74.6-93.3) | 90.0 (55.2-98.5) | 84.9 (77.2-90.3) |
- Citation: Packova B, Kovalcikova P, Pavlovsky Z, Bartusek D, Prokesova J, Dolina J, Kroupa R. Non-invasive prediction of persistent villous atrophy in celiac disease. World J Gastroenterol 2020; 26(26): 3780-3791
- URL: https://www.wjgnet.com/1007-9327/full/v26/i26/3780.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i26.3780