Type I and type II Helicobacter pylori infection status and their impact on gastrin and pepsinogen level in a gastric cancer prevalent area

Table 4 Effects of Helicobacter pylori infection on gastric gastrin-17, pepsinogen I, pepsinogen II levels and pepsinogen I/II ratios

H. pylori status	n	G-17, pmol/L	PG I, µg/L	PG II, µg/L	PG I/PG II
H. pylori (+)	402	7.9 ± 8.9a	131.4 ± 86.6	17.3 ±13.2a	8.4 ± 4.8a
H. pylori (-)	121	3.6 ± 5.2	117.0 ± 76.7	10.5 ± 9.2	12.8 ± 6.5
Type I H. pylori (+)	291	8.5 ± 9.5ac	134.2 ± 86.4	18.7 ± 13.7ac	7.7± 4.2ac
Type II H. pylori (+)	111	6.1 ± 6.5a	123.9 ± 86.9	13.9 ± 11.0	10.5 ± 5.6a

Data are presented as mean ± standard deviation.

^aP < 0.05, when compared with H. pylori-negative group;

^cP < 0.05, when compared between type I and type II H. pylori-infected groups. G-17: Gastrin-17; H. pylori: Helicobacter pylori; PG I: Pepsinogen I; PG I/PG II : Pepsinogen I/II ratio; PG II: Pepsinogen II.