Value of intravoxel incoherent motion in detecting and staging liver fibrosis: A meta-analysis

Table 3 Diagnostic raw data of intravoxel incoherent motion in each liver fibrosis group

Study	Index	Threshold1	TP	FP	FN	TN	SEN	SPE
LF ≥ F1
Chen et al[24], 2014	D*	17.52	20	7	5	18	0.80	0.72
Fu et al[25], 2019	Dt	0.63	75	3	24	23	0.76	0.88
Ichikawa et al[26], 2015	D*	72.15	96	10	14	62	0.87	0.86
Parente et al[28], 2015	D*	37.75	10	13	6	30	0.63	0.70
Wu et al[27], 2015	D*	51.30	27	0	16	6	0.63	1.00
LF ≥ F2
Fu et al[25], 2019	Dt	0.62	64	7	18	36	0.78	0.84
Hu et al[29], 2017	D*	32.10	30	8	1	17	0.97	0.68
Ichikawa et al[26], 2015	D*	71.72	91	14	6	71	0.94	0.84
Sandrasegaran et al[32], 2018	D*	23.40	31	4	6	8	0.84	0.67
Seo et al[31], 2018	D*	77.64	44	17	7	27	0.86	0.61
Wu et al[27], 2015	D*	40.90	16	3	11	19	0.59	0.86
Yoon et al[33], 2014	D*	43.33	31	0	6	18	0.84	1.00
Yoon et al[30], 2019	D*	70.70	67	2	20	17	0.77	0.89
Zawada et al[34], 2019	Dt	1.00	7	5	7	21	0.50	0.81
LF ≥ F3
Chung et al[35], 2015	f	0.28	20	5	9	23	0.69	0.82
Fu et al[25], 2019	Dt	0.58	40	16	9	60	0.82	0.79
Ichikawa et al[26], 2015	D*	65.04	78	14	5	85	0.94	0.86
Wu et al[27], 2015	D*	40.90	13	6	4	26	0.76	0.81
LF = F4
Fu et al[25], 2019	Dt	0.58	23	31	1	70	0.96	0.69
Hu et al[29], 2017	D*	14.44	8	3	2	43	0.80	0.93
Ichikawa et al[26], 2015	D*	61.97	58	24	6	94	0.91	0.80
Seo et al[31], 2018	D*	54.42	22	17	7	49	0.76	0.74
Wu et al[27], 2015	D*	40.30	7	15	0	27	1.00	0.64
Yoon et al[33], 2014	D*	44.17	21	12	0	22	1.00	0.65

¹The unit of Dt and D* is 10⁻³ mm²/s. LF: Liver fibrosis; TP: True positive; FP: False positive; FN: False negative; TN: True negative; SEN: Sensitivity; SPE: Specificity; Dt: True diffusion coefficient; D*: Pseudo-diffusion coefficient; f: Perfusion fraction.