Neoadjuvant chemoradiation changes podoplanin expression in esophageal cancer patients

Table 4 Expression of podoplanin protein differs between tissues resected from neoadjuvantly treated and non-pretreated direct surgery squamous cell carcinoma of the esophagus patients

Resected tissue	Podoplanin		Patients
	Score	%	n	%
RTx/CTx + surgery	1	0-5	51	89
	2	6-35	5	9
	3	36-65	2	2
Primary surgery non-pretreated	1	0-5	16	50
	2	6-35	11	34
	3	36-65	5	16

Resected tissue specimen: neoadjuvant chemoradiation squamous cell carcinoma of the esophagus (ESCC) patients, n = 58 and non-pretreated direct surgery ESCC patients, n = 32, scoring by immunohistochemically stained D2-40, P < 0.001. RTx/CTx: Neoadjuvant radio-/chemotherapy.