Gan Shen Fu Fang ameliorates liver fibrosis in vitro and in vivo by inhibiting the inflammatory response and extracellular signal-regulated kinase phosphorylation

Figure 1 Gan Shen Fu Fangdecreased serum levels of alanine aminotransferase, aspartate aminotransferase and total bilirubin in common bile duct-ligated rats and the liver and spleen coefficients (n = 8). A: Alanine aminotransferase level; B: Aspartate aminotransferase level; C: Total bilirubin level; D:Liver coefficient; E: Spleen coefficient. The data are presented as the mean ± SD. ^bP < 0.01, ^eP < 0.001, compared with the sham group; ^cP < 0.05, compared with the 2W-CBDL rats; ^gP < 0.05, ^kP < 0.001, compared with the 4W-CBDL rat. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; TBIL: Total bilirubin; CBDL: Common bile duct-ligated; GSFF: Gan Shen Fu Fang.