Use of zebrafish embryos as avatar of patients with pancreatic cancer: A new xenotransplantation model towards personalized medicine

Table 6 Calculation of the conversion factor for the test with xenotransplanted zebrafish embryos

	Study	Percentage of partial response reported in literature	Conversion Factor for xenotransplanted zebrafish embryos	Mean conversion factor (P = 0.626)
k vs FOLFOXIRI	Conroy et al[7], 2011	31	-60.1	-60.4
	Tong et al[40], 2018	35.9	-56.2
	Lakatos et al[41], 2017	18.8	-69.8
	Nitsche et al[42], 2015	42.8	-50.7
	Sadot et al[43], 2015	29	-61.7
	Wang et al[44], 2019	32.3	-59.1
k vs GEMOX	Shi et al[46], 2007	26.8	-55.2	-59.3
	Li et al[47], 2010	25	-56.8
k vs Gem/nab-P	Von Hoff et al[48], 2013	23	-61.3	-62.4
	Casanova-Martinez et al[49], 2018	20	-64.0
	Karasic et al[50], 2019	21.1	-63.0
	Montes et al[51], 2017	23	-61.3
k vs Gemcitabine	Conroy et al[7], 2011	16	-63.9	-63.7
	Louvet et al[52], 2005	17.3	-62.8
	Ergun et al[53], 2018	15.3	-64.5

k: Control group; GEM: Gemcitabine; GEMOX: Gemcitabine + Oxaliplatin; GEM/nab-P: Gemcitabine + nab-Paclitaxel; FOLFOXIRI: 5-Fluorouracil + Folinic acid + Oxaliplatin + Irinotecan.