Clinicopathological features of early gastric cancers arising in Helicobacter pylori uninfected patients

Figure 1 Fundic gland type adenocarcinoma. A: Cancer cells with enlarged nuclei formed irregular glands. The surface of the tumor was covered with non-cancerous epithelium, hematoxylin and eosin, original magnification 4 ×; B: The tumor invaded into the submucosal layer in a state that kept the muscularis mucosa. The distance from muscularis mucosa was 75 μm, hematoxylin and eosin, original magnification 40 ×; C: PG-I stains showed focal positive for cancer cells; D: The submucosal tumor like a small protrusion on the greater curvature of the upper gastric body, white light endoscopy; E: The surface of the tumor was covered with normal epithelium, magnifying endoscopy with narrow-band imaging.