Impact of GFRA1 gene reactivation by DNA demethylation on prognosis of patients with metastatic colon cancer

doi:10.3748/wjg.v26.i2.184

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2020; 26(2): 184-198
Published online Jan 14, 2020. doi: 10.3748/wjg.v26.i2.184

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Figure 4 GFRA1b overexpression promotes the proliferation of colon cancer cells in vitro. A: GFRA1 expression status in RKO and HCT116 cells transfected with the pLenti-empty control vector or pLenti-GFRA1b vector, determined by Western blot; B: Proliferation curves for RKO and HCT116 cells, determined using the IncuCyte systems; C: Migration curves for RKO and HCT116, determined using the IncuCyte systems. Error bars represent S.D.; ^bP < 0.01; D: Invasion curves for RKO and HCT116, determined using the IncuCyte systems. Error bars represent S.D.; ^aP < 0.05. Ctrl: Control.

Citation: Ma WR, Xu P, Liu ZJ, Zhou J, Gu LK, Zhang J, Deng DJ. Impact of GFRA1 gene reactivation by DNA demethylation on prognosis of patients with metastatic colon cancer. World J Gastroenterol 2020; 26(2): 184-198
URL: https://www.wjgnet.com/1007-9327/full/v26/i2/184.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i2.184