MiR-301a transcriptionally activated by HIF-2α promotes hypoxia-induced epithelial-mesenchymal transition by targeting TP63 in pancreatic cancer

Figure 6 MiR-301a overexpression promotes the metastasis of CFPAC-1 cells in vitro. A: Photographs of the orthotopic implantation of pancreatic cancer cells in nude mice; B: Tumor formation and metastasis were assessed with BLI measurements. Metastasis occurred in the miR-301a overexpression group; C: MiR-301a accelerated the local invasion, lymph node metastasis, and distant metastasis of pancreatic cancer cells; D: HE staining of tumor tissues and metastatic tissues.