Update on quinolone-containing rescue therapies for Helicobacter pylori infection

Table 2 Moxifloxacin-containing therapies

Ref.	Country	X-line	Publication year	Drug combination (per day)	Duration (d)	Eradication rate (%)
						ITT	PP
Cheon et al[70]	South Korea	2nd	2006	MOFX 400 mg + AMX 2000 mg + RPZ 40 mg	7	75.6	83.8
Kang et al[71]	South Korea	2nd	2007	MOFX 400 mg + AMX 2000 mg + EPZ 40 mg	10	71.9	82.6
Bago et al[72]	Croatia	2nd	2009	MOFX 400 mg + MTZ 1500 mg + OPZ 40 mg	7	73.2	78.9
Yoon et al[73]	South Korea	2nd	2009	MOFX 400 mg + AMX 2000 mg + EPZ 40 mg	7	75.6	83.8
Yoon et al[73]	South Korea	2nd	2009	MOFX 400 mg + AMX 2000 mg + EPZ 40 mg	10	71.9	82.6
Yoon et al[73]	South Korea	2nd	2009	MOFX 400 mg + AMX 2000 mg + EPZ 40 mg	14	68.0	79.9
Miehlke et al[74]	Germany	2nd and more	2011	MOFX 400 mg + AMX 2000 mg + EPZ 40 mg	7	78.9	78.9
Miehlke et al[74]	Germany	2nd and more	2011	MOFX 400 mg + AMX 2000 mg + EPZ 40 mg	14	95.0	94.4
Kang et al[75]	South Korea	2nd	2014	MOFX 400 mg + AMX 2000 mg + RPZ 20 mg	7	58.0	62.5
Kang et al[75]	South Korea	2nd	2014	MOFX 400 mg + AMX 2000 mg + RPZ 20 mg	14	71.8	77.5
Chung et al[77]	South Korea	2nd	2014	MOFX 400 mg + AMX 2000 mg + RPZ 40 mg	7	62.7	62.7
Lee et al[76]	South Korea	2nd	2015	MOFX 400 mg + AMX 2000 mg + PPI	7	53.1	55.6
Lee et al[76]	South Korea	2nd	2015	MOFX 400 mg + AMX 2000 mg + PPI	14	73.5	80.6
Hwang et al[78]	South Korea	2nd	2015	MOFX 400 mg + AMX 2000 mg + RPZ 40 mg	7	70.8	77.7
Hwang et al[78]	South Korea	2nd	2015	MOFX 400 mg + AMX 2000 mg + RPZ 40 mg	14	81.4	90.4
Lim et al[79]	South Korea	2nd	2015	MOFX 400 mg + AMX 2000 mg + RPZ 40 mg	7	56.7	59.6
Lim et al[79]	South Korea	2nd	2015	MOFX 400 mg + AMX 2000 mg + RPZ 40 mg	14	76.3	80.6
Marušić et al[81]	Croatia	2nd	2017	MOFX 400 mg + MTZ 1000 mg + Bismuth 480 mg + PPZ 80 mg	14	80.6	88.0

ITT: Intention-to-treat; PP: Per protocol; MOFX: Moxifloxacin; AMX: Amoxicillin; RPZ: Rabeprazole; EPZ: Esomeprazole; OPZ: Omeprazole; PPI: Proton pump inhibitors; PPZ: Pantoprazole; MTZ: Metronidazole.