Effects of long non-coding RNA Opa-interacting protein 5 antisense RNA 1 on colon cancer cell resistance to oxaliplatin and its regulation of microRNA-137

Figure 1 The expression of long non-coding RNA Opa-interacting protein 5 antisense RNA 1 and microRNA-137 in colon cancer. A: Opa-interacting protein 5 antisense RNA 1 (OIP5-AS1) was highly expressed in cancer tissues; B: miR-137 showed low expression in cancer tissues; C: The expression of OIP5-AS1 was negatively correlated with that of miR-137 in cancer tissues (r = - 0.7123); D: The value of OIP5-AS1 in diagnosing colon cancer (CC) patients; E: The value of miR-137 in diagnosing CC patients; F: The expression of OIP 5-AS1 in CC cell lines was much higher than that in the normal colon epithelial cell line; G: The expression of miR-137 in CC cell lines was significantly lower than that in the normal colon epithelial cell line. ^bP < 0.01, ^eP < 0.001 for between-group comparisons. OIP5-AS1: Opa-interacting protein 5 antisense RNA 1; LncRNA: Long non-coding RNA.