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©The Author(s) 2020.
World J Gastroenterol. Apr 7, 2020; 26(13): 1501-1512
Published online Apr 7, 2020. doi: 10.3748/wjg.v26.i13.1501
Published online Apr 7, 2020. doi: 10.3748/wjg.v26.i13.1501
Table 1 Correlation between gamma-glutamyltransferase to lymphocyte ratio and clinicopathological characteristics in intrahepatic cholangiocarcinoma
| Variables | Derivation | P value | Validation | P value | ||
| GLR ≤ 33.7 | GLR > 33.7 | GLR ≤ 33.7 | GLR > 33.7 | |||
| Total patients | 107 | 157 | 97 | 166 | ||
| Age, yr | 57.96 (11.48) | 57.80 (10.35) | 0.902 | 56.97 (10.69) | 56.48 (10.56) | 0.716 |
| Male gender, n (%) | 42 (39.3) | 85 (54.1) | 0.024a | 38 (39.2) | 89 (53.6) | 0.030a |
| HBsAg, n (%) | 36 (33.6) | 37 (23.6) | 0.073 | 31 (32.3) | 47 (28.5) | 0.575 |
| Hepatolithiasis, n (%) | 14 (13.1) | 27 (17.2) | 0.396 | 15 (15.5) | 32 (19.3) | 0.511 |
| Child-Pugh grade B, n (%) | 3 (2.8) | 8 (5.1) | 0.533 | 2 (2.1) | 11 (6.6) | 0.141 |
| Ascites, n (%) | 6 (5.6) | 21 (13.4) | 0.061 | 4 (4.1) | 19 (11.4) | 0.068 |
| CA-199 < 22, n (%) | 38 (36.5) | 42 (27.5) | 0.005a | 29 (31.2) | 40 (24.2) | 0.043a |
| Tumor size, cm | 5.14 (2.29) | 6.51 (2.78) | < 0.001a | 5.40 (2.22) | 6.36 (2.97) | 0.007a |
| Solitary tumor, n (%) | 89 (83.2) | 102 (65.0) | 0.001a | 67 (69.1) | 113 (68.1) | 0.895 |
| Well tumor differentiation, n (%) | 6 (5.6) | 4 (2.5) | 0.331 | 5 (5.2) | 7 (4.2) | 0.767 |
| Macrovascular invasion, n (%) | 17 (15.9) | 45 (28.7) | 0.011a | 8 (8.2) | 53 (31.9) | < 0.001a |
| Microvascular invasion, n (%) | 6 (5.6) | 23 (14.6) | 0.026a | 7 (7.2) | 17 (10.2) | 0.514 |
| Liver capsule invasion, n (%) | 67 (62.6) | 107 (68.2) | 0.362 | 64 (66.0) | 97 (58.4) | 0.248 |
| Node-positive, n (%) | 16 (15.0) | 48 (30.6) | 0.005a | 18 (18.6) | 47 (28.3) | 0.107 |
| Perineural invasion, n (%) | 9 (8.4) | 27 (17.2) | 0.044a | 8 (8.2) | 35 (21.1) | 0.009a |
| Cirrhosis, n (%) | 27 (25.2) | 53 (33.8) | 0.174 | 19 (19.6) | 46 (27.7) | 0.182 |
| TNM stage, n (%) | 0.002a | 0.107 | ||||
| IA | 23 (21.5) | 12 (7.6) | 13 (13.4) | 15 (9.0) | ||
| IB | 6 (5.6) | 12 (7.6) | 6 (6.2) | 13 (7.8) | ||
| II | 6 (5.6) | 13 (8.3) | 10 (10.3) | 26 (15.7) | ||
| IIIA | 55 (51.4) | 72 (45.9) | 50 (51.5) | 64 (38.6) | ||
| IIIB | 17 (15.9) | 48 (30.6) | 18 (18.6) | 48 (28.9) | ||
| BCLC stage, n (%) | < 0.001a | < 0.001a | ||||
| 0 | 6 (5.6) | 9 (5.7) | 3 (3.1) | 5 (3.0) | ||
| A | 44 (41.1) | 25 (15.9) | 34 (35.1) | 38 (22.9) | ||
| B | 40 (37.4) | 78 (49.7) | 52 (53.6) | 70 (42.2) | ||
| C | 17 (15.9) | 45 (28.7) | 8 (8.2) | 53 (31.9) | ||
- Citation: Wang JJ, Li H, Li JX, Xu L, Wu H, Zeng Y. Preoperative gamma-glutamyltransferase to lymphocyte ratio predicts long-term outcomes in intrahepatic cholangiocarcinoma patients following hepatic resection. World J Gastroenterol 2020; 26(13): 1501-1512
- URL: https://www.wjgnet.com/1007-9327/full/v26/i13/1501.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i13.1501