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©The Author(s) 2020.
World J Gastroenterol. Mar 28, 2020; 26(12): 1329-1339
Published online Mar 28, 2020. doi: 10.3748/wjg.v26.i12.1329
Published online Mar 28, 2020. doi: 10.3748/wjg.v26.i12.1329
Table 2 Demographic and clinical features of Polygonum multiflorum-induced liver injury patients and other drug-induced liver injury patients
Characteristics | PM-DILI (n = 73) | Other-DILI (n = 118) | P |
Mean age, yr | 47.7 ± 15.8 | 52.3 ± 14.2 | 0.045 |
Female, n (%) | 56 (76.7) | 74 (62.7) | 0.044 |
BMI | 23.6 ± 3.2 | 24.0 ± 3.7 | 0.447 |
Medication time1, d | 30 (45) | 30 (60.8) | 0.097 |
ALT (U/L) | 1105.0 ± 679.9 | 626.3 ± 670.1 | < 0.001 |
AST (U/L), n | 797.7 ± 557.3 (65) | 485.6 ± 596.5 (118) | 0.001 |
ALP (U/L), n | 148.5 ± 58.4 (59) | 160.5 ± 212.3 (105) | 0.673 |
TBil (mg/dL), n | 112.9 ± 107.2 (61) | 76.9 ± 92.5 (99) | 0.026 |
Injury type | n = 59 | n = 105 | 0.917 |
Hepatocellular | 57 | 82 | |
Cholestatic | 1 | 12 | |
Mixed | 1 | 11 | |
RUCAM score | 0.319 | ||
3-5 (Possible) | 7 | 20 | |
6-8 (Probable) | 53 | 82 | |
≥ 9 (Highly probable) | 13 | 16 |
- Citation: Yang WN, Pang LL, Zhou JY, Qiu YW, Miao L, Wang SY, Liu XZ, Tan KA, Shi WW, Wang GQ, Hou FQ. Single-nucleotide polymorphisms of HLA and Polygonum multiflorum-induced liver injury in the Han Chinese population. World J Gastroenterol 2020; 26(12): 1329-1339
- URL: https://www.wjgnet.com/1007-9327/full/v26/i12/1329.htm
- DOI: https://dx.doi.org/10.3748/wjg.v26.i12.1329