Prognostic factors and predictors of postoperative adjuvant transcatheter arterial chemoembolization benefit in patients with resected hepatocellular carcinoma

Table 3 Identification of prognostic factors for overall survival based on multivariate analysis of the matched data

	PA-TACE			Surgery Alone
Characteristic	Hazard ratio	95%CI	P value	Hazard ratio	95%CI	P value
Age (yr)			0.023			-
< 65	Reference			-	-	-
≥ 65	0.257	0.080-0.826	0.023	-	-	-
Gender			-			0.027
Male	-	-	-	Reference
Female	-	-	-	0.523	0.294-0.930	0.027
BCLC stage			0.021			0.036
0	Reference			Reference
A	3.972	1.23-12.825	0.021	1.963	1.044-3.689	0.036
HBV			-			0.034
Negative	-	-	-	Reference
Positive	-	-	-	1.982	1.013-4.736	0.034
MVI			0.002			-
No	Reference			-	-	-
Yes	2.850	1.475-5.506	0.002	-	-	-
ALBI grade			-			0.027
1	-	-	-	Reference
2	-	-	-	1.732	1.064-2.821	0.027
3	-	-	-	-	-	-
FHR			< 0.001			< 0.001
≤ Median	Reference			Reference
> Median	3.338	1.810-6.157	< 0.001	1.963	1.044-3.689	< 0.001

PA-TACE: Postoperative adjuvant transcatheter arterial chemoembolization; BMI: Body mass index; BCLC: Barcelona Clinic Liver Cancer system; HBV: Hepatitis B virus; MVI: Microscopic vascular invasion; ALBI: Albumin-bilirubin; FHR: Ferritin-to-hemoglobin ratio.