Risk of gastrointestinal cancer in a symptomatic cohort after a complete colonoscopy: Role of faecal immunochemical test

Table 2 Characteristics of the individuals included in the analysis, n (%)

Characteristics	Overall (n = 2709)	FIT < 10 µg/g (n = 1979)	FIT ≥ 10 µg/g (n = 730)	P value8
Demographic
Age (yr)	62.9 ± 13.5	62.0 ± 13.5	65.5 ± 13.0	< 0.001
Female sex	1432 (52.9)	1084 (54.8)	348 (47.7)	0.001
Primary healthcare referral1	617 (24.2)	397 (21.2)	220 (32.2)	< 0.001
Previous colonoscopy2	444 (25.9)	287 (25.8)	157 (26.0)	0.9
Daily using ASA2	330 (19.2)	193 (17.3)	137 (22.7)	0.01
Indications
Rectal bleeding1	1234 (48.3)	843 (45.1)	391 (57.2)	< 0.001
Change of bowel habit1	1271 (49.8)	913 (48.8)	358 (52.4)	0.1
Anaemia3,4	368 (16.2)	236 (13.9)	132 (23.1)	< 0.001
Abdominal pain5	766 (41.3)	587 (41.8)	179 (40.0)	0.4
Weight loss5	391 (21.1)	301 (21.4)	90 (20.1)	0.6
Basal colonoscopy findings
Benign anorectal lesion2	756 (44.0)	495 (44.4)	261 (43.3)	0.6
Significant colonic lesions6	480 (17.7)	204 (10.3)	276 (37.8)	< 0.001
Advanced adenoma1,7	337 (13.2)	139 (7.4)	198 (29.0)	< 0.001
Follow-up (mo)	45.5 ± 20.0	47.9 ± 21.2	39.2 ± 14.1	< 0.001

Missing data in

¹156,

²992,

³441 and

⁴Defined as < 11 g/100 mL in men and < 10 g/100 mL in non-menstruating women.

⁵856 patients.

⁶Advanced adenoma (≥ 10 mm, villous histology, high-grade dysplasia), polyposis (> 10 polyps of any histology), colitis (any aetiology), polyps ≥ 10 mm, complicated diverticular disease, colonic ulcer and/or bleeding angiodysplasia.

⁷Adenoma ≥ 10 mm, villous histology or high-grade dysplasia.

⁸Differences between both groups in the Chi-square test in the qualitative variables and in the student t test in the quantitative variables. Differences with P < 0.05 are considered statistically significant. Qualitative variables are expressed as absolute numbers and percentages. Quantitative variables are expressed as mean and standard deviation. ASA: Acetyl salicylic acid; FIT: Faecal immunochemical test.