Effect of Endocuff use on colonoscopy outcomes: A systematic review and meta-analysis

Table 1 Characteristics of included studies

Author (yr)	Country	Study period	Centres, n	Endoscopists, n	Device	Endoscopes	Patients, n	EAC/CC, n/n	Indication	Female EAC/CC, n (%)	Age EAC/CC, mean ± SD	Screening EAC/CC, n (%)	Bowel Preparation EAC/CC
Floer et al[15]	Germany	02.2014-07.2014	4	10	Endocuff	HD	492	249/243	Mixed	127 (51)/134 (55.1)	64 ± 3.2/63 ± 3.3	NR	11 (1-2)/1 (1-2) [median (IQR)]
Van Doorn et al[16]	Netherlands	08.2013-10.2014	5	20	Endocuff	HD	1063	530/533	Mixed	266 (50.2)/248 (46.5)	65 ± 2.2/65 ± 2.3	201 (37.9)/197 (36.9)	29 (7-9)/8 (7-9) [median (IQR)]
Biecker et al[17]	Germany	02.2013-08.2013	2	6	Endocuff	HD	498	245/253	Mixed	127 (51.8)/122 (48.2)	65 ± 3.3/68 ± 3	NR	169% good/65% good
De Palma et al[18]	Italy	02.2015 -03.2016	1	4	Endocuff	HD	274	137/137	Mixed	66 (48.2)/65 (47.4)	55 ± 12.6/55.7 ± 12.3	32 (23.4)/29 (21.2)	7.08 ± 1.06/7.18 ± 0.97 [mean ± SD]
Bhattacharyya et al[19]	United Kingdom	09.2014-09.2015	1	4	Endocuff Vision	HD	531	266/265	FOBT (+) screening, surveillance	104 (39.1)/85 (32.1)	68 ± 1.2/67 ± 1.2	180 (70.7)/186 (69.1)	3Good/adequate 97.7% /Good adequate 97.7%
González-Fernández et al[20]	Mexico	04.2014-11.2015	1	18	Endocuff	Mixed	337	174/163	Screening	124 (71)/124 (76)	60 ± 1.8/62 ± 2.5	174 (100)/163 (100)	27 (6-8)/7 (6-8) [median (IQR)]
Ngu et al[21]	United Kingdom	11.2014-02.2016	7	48	Endocuff Vision	Not reported	1772	888/884	FOBT (+) screening, surveillance	381 (42.9)/ 382 (43.2)	61.7 ± 11.7/62.1 ± 11.1	274 (30.9)/282 (32)	NR
Wada et al[22]	Japan	04.2015-09.2015	1	1	Endocuff	HD	477	239/238	Mixed	117 (48.9)/123 (51.7)	61.2 ± 3.3/62.2 ± 3.3	89 (37.2)/74 (31.1)	27.91 ± 0.94/7.88 ± 1.03 [mean ± SD]
Rex et al[23]	United States, Italy	NR	3	3	Endocuff	HD	594	299/295	Mixed	141 (47) /141 (47)	63.2 ± 8.2/62.6 ± 8.3	126 (42)/127 (43)	28.12 ± 1.33 overall, no differences between the 2 groups

¹Based on Leighton et al[25] scale (1 = good; 2 = fair; 3 = poor);

²Boston Bowel Preparation Scale[24] ;

³Based in Rees et al[26] scale. EAC: Endocuff-assisted colonoscopy; CC: Conventional colonoscopy; HD: High definition; SD: Standard deviation; FOBT: Fecal occult blood test; Mixed: Screening, surveillance and diagnostic cases.