Conventional therapy for moderate to severe inflammatory bowel disease: A systematic literature review

Table 4 Meta-analyses included for induction of clinical response in Crohn’s disease

Study	Intervention	Comparator	Follow-up	n	Clinical response, RR (95%CI)	Quality of evidence
Chande et al[23]	AZA or 6-MP	Placebo	6 wk-9 mo	434	RR 1.26 (0.98-1.62)1	Moderate

¹Clinical response considered the outcomes of remission and improvement and varied from study to study making exact comparisons across studies difficult. Therefore, the definition of improvement or remission used in each study was used for data extraction. 6-MP: 6-mercaptopurine; AZA: azathioprine; CI: Confidence interval; n: Number of patients; RR: Risk ratio.