Comprehensive lifestyle intervention vs soy protein-based meal regimen in non-alcoholic steatohepatitis

Table 2 Comparison of changes in parameters

Change in	Group				P between groups
	Meal replacement		Lifestyle change
	Median	IQR	Median	IQR
Weight (kg)	-6.4	3.6	-9.1b	10.4	0.48
BMI (kg/m2)	-2.3b	1.5	-3.0b	3.4	0.48
Waist circumference (cm)	-4.0b	5.0	-7.0b	10.5	0.65
AST (U/L)	-4.0a	14.0	-15.0a	14.0	0.30
ALT (U/L)	-8.0b	22.0	-18.0b	35.0	0.19
Glucose (mg/dL)	-10.0	20.0	-20.0a	31.0	0.70
HbA1c (%)	-0.1	0.4	-0.3a	0.3	0.65
Creatinine (mg/dL)	0.0	0.1	0.0	0.1	0.56
Cholesterol (mg/dL)	-8.0	29.0	-3.0	44.5	0.99
HDL-Cholesterol (mg/dL)	2.9	10.1	1.4	11.1	0.40
LDL-Cholesterol (mg/dL)	3.9	22.1	6.8	29.0	0.61
Triglycerides (mg/dL)	-43.0a	137.0	-9.0	74.5	0.65
Adiponectin (µg/mL)	0.3a	1.1	0.1	2.9	0.48
Leptin (ng/mL)	-2.4a	3.5	-12.8a	15.1	0.27
Vaspin (mg/mL)	0.0	0.1	0.0	0.3	0.70
Fetuin A (g/L)	0.0	0.1	0.0	0.0	0.85
Resistin (ng/mL)	-0.1	2.0	0.2	1.3	0.95
Max. Performance (Watt/kg)	0.0	29.8	6.3a	21.9	0.03
Fat mass (kg)	-6.0b	4.2	-9.3b	11.1	0.30
Lean body mass (kg)	0.0	1.7	-0.7	2.0	0.95
MRI subcutaneous fat (kg)	-1.1a	0.9	-2.0b	3.1	0.06
MRI internal fat (kg)	-0.5	0.9	-0.9b	1.1	0.09
MRI total fat (kg)	-1.6	2.2	-3.0b	4.2	0.06
Intrahepatic lipid content	-10.3b	8.4	-11.8a	15.4	0.20
Saturated lipid component	-5.1	7.0	-2.0a	4.1	0.92
Total unsaturated lipid comp.	-2.0b	1.0	0.2	4.9	0.05
Fraction unsaturated lipids	-0.1	0.2	0.0	0.3	0.61
Mean chain length	-8.0a	6.2	-1.4	10.0	0.03

^aP < 0.05 or

^bP < 0.01 for changes within the group.