Triggers of histologically suspected drug-induced colitis

Table 6 Binary logistic regression analysis

Parameter	Drug-induced colitis vs inflammatory controls OR (95%CI)	Drug-induced colitis vs non-inflammatory controls OR (95%CI)
Heart failure	0.6 (0.3-1.1)	1.3 (0.6-2.8)
Atherosclerosis	2.1 (1.2-3.7)b	1.7 (0.9-3.1)
Dihydropyridines	1.3 (0.7-2.5)	1.0 (0.5-1.8)
Diuretics	1.5 (0.8-2.6)	1.7 (1.0-3.0)
Digitalis glycosides	1.1 (0.4-3.1)	3.7 (0.8-17.9)
Low-dose ASS	1.7 (1.0-2.8)	1.1 (0.7-1.9)
Platelet aggregation inhibitors	2.0 (0.7-5.7)	1.4 (0.6-3.3)
NSAIDs	6.7 (3.0-15.1)b	2.2 (1.2-4.0)a
Statins	1.1 (0.6-1.9)	0.9 (0.6-1.6)
Fibrates	9.1 (1.1-74.3)a	8.9 (1.1-74.2)a

^aP < 0.05.

^bP < 0.01.

NSAIDs: Nonsteroidal anti-inflammatory drugs.