Copyright
©The Author(s) 2019.
World J Gastroenterol. Feb 28, 2019; 25(8): 941-954
Published online Feb 28, 2019. doi: 10.3748/wjg.v25.i8.941
Published online Feb 28, 2019. doi: 10.3748/wjg.v25.i8.941
Table 1 The most prominent metabolites
No. | Ret. time | m/z | Adduct | Compound | Independent t-test | |||
Con vs Week 1 | Con vs Week 4 | Con vs Week 8 | Con vs Week 12 | |||||
1 | 18.6 | 786.6003 | [M+H]+ | PC(18:0/18:2) | 0.045 | 0.005 | 0.001 | 0.338 |
2 | 18.47 | 810.5999 | [M+H]+ | PC(18:0/20:4) | 0.000 | 0.000 | 0.000 | 0.000 |
3 | 18.34 | 760.5851 | [M+H]+ | PC(16:0/18:1) | 0.130 | 0.206 | 0.000 | 0.363 |
4 | 18.29 | 834.6003 | [M+H]+ | PC(18:0/22:6) | 0.000 | 0.002 | 0.071 | 0.000 |
5 | 17.73 | 758.5689 | [M+H]+ | PC(16:0/18:2) | 0.499 | 0.526 | 0.001 | 0.000 |
6 | 17.61 | 782.569 | [M+H]+ | PC(18:2/18:2) | 0.000 | 0.000 | 0.001 | 0.000 |
7 | 17.49 | 806.5689 | [M+H]+ | PC(22:6/16:0) | 0.000 | 0.037 | 0.808 | 0.439 |
8 | 17.31 | 782.5693 | [M+H]+ | PC(16:0/20:4) | 0.021 | 0.000 | 0.000 | 0.000 |
9 | 17.2 | 806.5676 | [M+H]+ | PC(18:2/20:4) | 0.000 | 0.041 | 0.000 | 0.000 |
10 | 17.13 | 756.5521 | [M+H]+ | PC(16:1/18:2) | 0.477 | 0.033 | 0.003 | 0.000 |
11 | 12.94 | 524.3707 | [M+H]+ | LysoPC(18:0) | 0.000 | 0.000 | 0.000 | 0.001 |
12 | 12.62 | 524.3714 | [M+H]+ | LysoPC(18:0) | 0.000 | 0.001 | 0.003 | 0.335 |
13 | 11.62 | 496.3383 | [M+H]+ | LysoPC(16:0) | 0.170 | 0.000 | 0.000 | 0.000 |
14 | 11.6 | 991.6714 | [2M+H]+ | LysoPC(16:0) | 0.003 | 0.639 | 0.789 | 0.000 |
15 | 11.03 | 544.3396 | [M+H]+ | LysoPC(20:4) | 0.000 | 0.000 | 0.000 | 0.003 |
16 | 10.75 | 544.3382 | [M+H]+ | LysoPC(20:4) | 0.000 | 0.000 | 0.000 | 0.000 |
17 | 9.12 | 373.2716 | M+H | Cervonoyl ethanolamide | 0.035 | 0.009 | 0.000 | 0.000 |
18 | 9.11 | 817.5807 | 2M+H | β-muricholic acid | 0.030 | 0.041 | 0.001 | 0.004 |
19 | 3.34 | 188.0702 | M+H | Indoleacrylic acid | 0.253 | 0.009 | 0.000 | 0.000 |
20 | 2.71 | 120.0802 | M+H | L-threonine | 0.026 | 0.000 | 0.000 | 0.000 |
21 | 0.97 | 120.0799 | M+H | Hydroxyethyl glycine | 0.008 | 0.007 | 0.000 | 0.000 |
- Citation: Yu J, He JQ, Chen DY, Pan QL, Yang JF, Cao HC, Li LJ. Dynamic changes of key metabolites during liver fibrosis in rats. World J Gastroenterol 2019; 25(8): 941-954
- URL: https://www.wjgnet.com/1007-9327/full/v25/i8/941.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i8.941