Lethal-7-related polymorphisms are associated with susceptibility to and prognosis of gastric cancer

Table 4 Genotypes of single nucleotide polymorphisms and overall survival of gastric cancer patients

SNP	Genotype	Total	Death (%)	5-yr survival rate	Median survival time	P valuea
rs13293512	T/T	213	100 (46.9)	51.6%	85.2	0.508
	T/C	370	172 (46.5)	53.3%	75.8
	C/C	148	60 (40.5)	59.0%	-b
rs562052	G/G	313	150 (47.9)	51.5%	76.2	0.253
	G/A	337	141 (41.8)	56.9%	-b
	A/A	77	40 (51.9)	50.7%	65.4
rs547008	C/C	434	200 (46.1)	53.0%	85.2	0.148
	C/T	264	112 (42.4)	56.2%	-b
	T/T	34	21 (61.8)	46.7%	33.8
rs1143770	T/T	215	98 (45.6)	54.3%	-b	0.535
	T/C	370	164 (44.3)	54.4%	-b
	C/C	138	68 (49.3)	51.3%	65.4
rs629367	A/A	435	205 (47.1)	52.8%	75.8	0.834
	A/C	264	113 (42.8)	55.6%	-b
	C/C	36	16 (44.4)	55.8%	85.2
rs10877887	T/T	301	147 (48.8)	50.4%	64.7	0.235
	T/C	330	141 (42.7)	57.2%	-b
	C/C	88	39 (44.3)	53.7%	-b
rs3811463	T/T	555	251 (45.2)	53.7%	85.2	0.971
	T/C	162	75 (46.3)	54.9%	77.7
	C/C	18	8 (44.4)	52.0%	-b
rs10889677	A/A	379	158 (41.7)	57.7%	-b	0.049
	A/C	301	146 (48.5)	50.3%	65.4
	C/C	53	30 (56.6)	46.0%	41.0
rs7963551	T/T	508	236 (46.5)	52.56%	85.2	0.144
	T/G	199	82 (41.2)	59.35%	-b
	G/G	27	16 (59.3)	38.22%	41.3
rs712	G/G	452	215 (47.6)	51.51%	73.7	0.227
	G/T	235	95 (40.4)	58.64%	-b
	T/T	36	17 (47.2)	55.01%	77.7

^aP was computed by log-rank test.

^bMedian survival time could not be estimated as fewer than 50% of patients died.