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©The Author(s) 2019.
World J Gastroenterol. Feb 28, 2019; 25(8): 1012-1023
Published online Feb 28, 2019. doi: 10.3748/wjg.v25.i8.1012
Published online Feb 28, 2019. doi: 10.3748/wjg.v25.i8.1012
Table 4 Genotypes of single nucleotide polymorphisms and overall survival of gastric cancer patients
SNP | Genotype | Total | Death (%) | 5-yr survival rate | Median survival time | P valuea |
rs13293512 | T/T | 213 | 100 (46.9) | 51.6% | 85.2 | 0.508 |
T/C | 370 | 172 (46.5) | 53.3% | 75.8 | ||
C/C | 148 | 60 (40.5) | 59.0% | -b | ||
rs562052 | G/G | 313 | 150 (47.9) | 51.5% | 76.2 | 0.253 |
G/A | 337 | 141 (41.8) | 56.9% | -b | ||
A/A | 77 | 40 (51.9) | 50.7% | 65.4 | ||
rs547008 | C/C | 434 | 200 (46.1) | 53.0% | 85.2 | 0.148 |
C/T | 264 | 112 (42.4) | 56.2% | -b | ||
T/T | 34 | 21 (61.8) | 46.7% | 33.8 | ||
rs1143770 | T/T | 215 | 98 (45.6) | 54.3% | -b | 0.535 |
T/C | 370 | 164 (44.3) | 54.4% | -b | ||
C/C | 138 | 68 (49.3) | 51.3% | 65.4 | ||
rs629367 | A/A | 435 | 205 (47.1) | 52.8% | 75.8 | 0.834 |
A/C | 264 | 113 (42.8) | 55.6% | -b | ||
C/C | 36 | 16 (44.4) | 55.8% | 85.2 | ||
rs10877887 | T/T | 301 | 147 (48.8) | 50.4% | 64.7 | 0.235 |
T/C | 330 | 141 (42.7) | 57.2% | -b | ||
C/C | 88 | 39 (44.3) | 53.7% | -b | ||
rs3811463 | T/T | 555 | 251 (45.2) | 53.7% | 85.2 | 0.971 |
T/C | 162 | 75 (46.3) | 54.9% | 77.7 | ||
C/C | 18 | 8 (44.4) | 52.0% | -b | ||
rs10889677 | A/A | 379 | 158 (41.7) | 57.7% | -b | 0.049 |
A/C | 301 | 146 (48.5) | 50.3% | 65.4 | ||
C/C | 53 | 30 (56.6) | 46.0% | 41.0 | ||
rs7963551 | T/T | 508 | 236 (46.5) | 52.56% | 85.2 | 0.144 |
T/G | 199 | 82 (41.2) | 59.35% | -b | ||
G/G | 27 | 16 (59.3) | 38.22% | 41.3 | ||
rs712 | G/G | 452 | 215 (47.6) | 51.51% | 73.7 | 0.227 |
G/T | 235 | 95 (40.4) | 58.64% | -b | ||
T/T | 36 | 17 (47.2) | 55.01% | 77.7 |
- Citation: Jia ZF, Cao DH, Wu YH, Jin MS, Pan YC, Cao XY, Jiang J. Lethal-7-related polymorphisms are associated with susceptibility to and prognosis of gastric cancer. World J Gastroenterol 2019; 25(8): 1012-1023
- URL: https://www.wjgnet.com/1007-9327/full/v25/i8/1012.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i8.1012