Relationships among KRAS mutation status, expression of RAS pathway signaling molecules, and clinicopathological features and prognosis of patients with colorectal cancer

doi:10.3748/wjg.v25.i7.808

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Feb 21, 2019 (publication date) through Jul 5, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2019; 25(7): 808-823
Published online Feb 21, 2019. doi: 10.3748/wjg.v25.i7.808

Table 6 Correlation between the expression of KRAS and downstream proteins

Protein		KRAS protein positive group	KRAS protein negative group	χ²	P-value
BRAF	76.4% (107/140)		69.6% (39/56)	0.964	0.325
MEK	78.6% (99/126)		58.6% (41/70)	8.775	0.003
ERK	69.6% (78/112)		39.3% (22/56)	4.298	0.038

Citation: Wan XB, Wang AQ, Cao J, Dong ZC, Li N, Yang S, Sun MM, Li Z, Luo SX. Relationships among KRAS mutation status, expression of RAS pathway signaling molecules, and clinicopathological features and prognosis of patients with colorectal cancer. World J Gastroenterol 2019; 25(7): 808-823
URL: https://www.wjgnet.com/1007-9327/full/v25/i7/808.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i7.808