Relationships among KRAS mutation status, expression of RAS pathway signaling molecules, and clinicopathological features and prognosis of patients with colorectal cancer

doi:10.3748/wjg.v25.i7.808

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2019; 25(7): 808-823
Published online Feb 21, 2019. doi: 10.3748/wjg.v25.i7.808

Table 5 Relationship between KRAS genotype and expression of downstream proteins in colorectal cancer tissues

Protein	KRAS mutant type group positive rate	KRAS wild-type group positive rate	χ²	P-value
BRAF	74.2% (46/62)	74.6% (100/134)	0.004	0.948
MEK	54.8% (34/62)	58.2% (78/134)	0.196	0.657
ERK	45.2% (28/62)	54.1% (72/133)	1.364	0.243

Citation: Wan XB, Wang AQ, Cao J, Dong ZC, Li N, Yang S, Sun MM, Li Z, Luo SX. Relationships among KRAS mutation status, expression of RAS pathway signaling molecules, and clinicopathological features and prognosis of patients with colorectal cancer. World J Gastroenterol 2019; 25(7): 808-823
URL: https://www.wjgnet.com/1007-9327/full/v25/i7/808.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i7.808