Claudin-7 gene knockout causes destruction of intestinal structure and animal death in mice

Figure 1 Strategic design and final vector sequencing results. A: Schematic diagram of the Cldn7 gene knockout targeting vector; B-D: The first and second regions in red show the sequencing results at LoxP and FRT 5’, while the grey region shows the FRT 3’ sequencing results; B-D indicate that the Cldn7 targeting vector was correct. Cldn7: Claudin-7.