Fatigue in children and adolescents with inflammatory bowel disease

Table 3 Description of fatigue-related diagnostic tests

Abbreviation	Full name	Details
CBCL	Child Behavior Checklist	Caregiver report form that categorizes problem behaviors in preschool and school-aged children in the following 8 syndromes: aggressive, anxious-depressed, attention, rule-breaking, somatic complaints, social, thought, withdrawn-depressed.
CDI	Children’s Depression Inventory	Adolescent self-reported assessment. For each of 26 items, respondents endorsed one of three sentences indicating varying levels of depression.
IMPACT-III	Not applicable	IBD disease-specific health-related quality-of-life questionnaire for pediatric patients. It is composed of 35 items in the following 6 domains: IBD-related symptoms (7 items), systemic symptoms (3), emotional functioning (7), social functioning (12), body image (3) and treatment/intervention-related concerns (3). Each item is scored on a 5-point Likert scale, coded from 0 to 4 points. Higher scores indicate better quality of life.
KIDSCREEN 27	Not applicable	Self-reported survey is a quality of life questionnaire consisting of 27 items measuring physical well-being, psychological well-being, autonomy and parent relations, peers and social support, and school environment.
KINDL	Not applicable	Adolescent self-reported survey consists of 24 Likert-scaled items, which are subdivided into the following six dimensions (subscales) of quality of life: physical well-being, emotional well- being; self-worth, well-being in the family, well-being regarding friendships and well-being at school.
McMaster Family Assessment Device	Not applicable	Adolescent self-reported 60-item instrument that assesses six domains, namely, problem solving, communication, roles, affective responsiveness, affective involvement, behavior control and general functioning of family functioning as well as general family dysfunction.
PedsQL generic scale	Pediatric Quality of Life Inventory	Parent reported and self-reported assessment. A modular approach to measuring health-related quality of life (HRQOL) in healthy children and adolescents and those with acute and chronic health conditions. It contains the following four multidimensional scales: physical functioning, emotional functioning, social functioning, school functioning.
PedsQL Multidimensional Fatigue Scale	Pediatric Quality of Life Inventory Multidimensional Fatigue Scale	Age-appropriate versions and parallel forms for children and parents. It measures the perceptions of fatigue by children and their parents and has been validated in a variety of pediatric chronic diseases.
RCMAS	Revised Children’s Manifest Anxiety scale	Adolescent self-reported assessment that is a true/false anxiety measure containing 28 items. The measured key areas are physiological anxiety, worry, social anxiety and defensiveness. The scale differentiates between anxiety-disordered and normal Children.
SSR	Sleep Self Report	Adolescent self-reported assessment to discern sleep patterns and possible difficulties with sleep.
TACQOL	TNO-AZL Children’s Quality of life Questionnaire	Generic health-related quality of life questionnaire enabling comparisons between groups of children with varying chronic diseases. It includes 7 scales, involving general physical function, motor function, daily function, cognitive function, social contact, and positive and negative moods.
YSR	Youth Self Report	Adolescent self-reported assessment with the following eight empirically-based syndrome scales: anxious/depressed, withdrawn/depressed and somatic complaints composing the internalizing (i.e., emotional) broad-band scale; rule-breaking behavior and aggressive behavior composing the externalizing (i.e., behavioral) broad-band scale; and these two scales, together with the syndrome scales of social, thought and attention problems, compose the total problems scale.