Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating tumor DNA

doi:10.3748/wjg.v25.i48.6939

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 28, 2019; 25(48): 6939-6948
Published online Dec 28, 2019. doi: 10.3748/wjg.v25.i48.6939

Table 3 Correlation of surgical radicality and postoperative circulating tumor DNA

	Number	State (time to recurrence or follow-up time)
R0	28
ctDNA positive	2	2 recurrence (6 mo)
ctDNA negative	26	10 no recurrence (6-36 mo), 14 recurrence (4-22 mo)¹
R1	7
ctDNA positive	4	4 recurrence (3-7 mo)
ctDNA negative	3	1 no recurrence (5 mo), 2 recurrence (7 or 22 mo)
R2	15
ctDNA positive	15	12/2/1 metastasis/primary tumor/both present
ctDNA negative	0	-

¹In two ctDNA negative R0 surgeries were missing follow-up information. ctDNA: Circulating tumor DNA; R0: Complete resection; R1: Microscopically incomplete resection; R2: Macroscopically incomplete resection.

Citation: Benešová L, Hálková T, Ptáčková R, Semyakina A, Menclová K, Pudil J, Ryska M, Levý M, Šimša J, Pazdírek F, Hoch J, Blaha M, Minárik M. Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating tumor DNA. World J Gastroenterol 2019; 25(48): 6939-6948
URL: https://www.wjgnet.com/1007-9327/full/v25/i48/6939.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i48.6939