Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating tumor DNA

Table 2 Clinical patient data

Characteristics		Value
Number of patients		47
Age	mean, range (yr)	63.6 ± 12.3, 32-87
Gender	Female/male	16/31
Localization of primary	Rectum	13
	Colon	14
	Rectosigmoid	8
	Sigmoid	7
	Cecum	3
	Others	2
Localization of metastasis	Liver only	35
	Liver and/or other	12
Surgical treatment
Number of surgeries1		63
Synchronous mCRC	Combined (primary and liver)	12
	Primary before metastases	8
	Liver first	2
	Liver in the second stage	14
Metachronous mCRC	Liver	24
	Other metastases	3
Radicality	R0	40
	R1	7
	R2	16
Recurrence (R0 surgeries)	Number2	27
	Mean time to reccurence, range (mo)	9.0 ± 5.1, 3-22

¹Postoperative ctDNA was available for 50 surgeries.

²All parameters for recurrence evaluation were available for 22 R0 surgeries. mCRC: Metastatic colorectal cancer; R0: Complete resection; R1: Microscopically incomplete resection; R2: Macroscopically incomplete resection.