Diagnostic and prognostic value of lncRNA cancer susceptibility candidate 9 in hepatocellular carcinoma

Table 4 Multivariate Cox regression analysis

Factors	Univariate Cox			Multivariate Cox
	P value	HR	95%CI	P value	HR	95%CI
Gender (male vs female)	0.272	1.320	1.320-0.804
Age (< 55 yr vs ≥ 55 yr)	0.438	0.825	0.825-0.508
Tumor size (≥ 5 cm vs < 5 cm)	0.952	1.015	1.015-0.624
Combined hepatitis (yes vs no)	0.636	1.185	1.185-0.586
TNM staging (stage I+II vs stage III+IV)	0.000	4.271	4.271-2.391	0.006	2.501	1.308-4.781
Lymph node metastasis (yes vs no)	0.001	0.428	0.428-0.259	0.025	0.535	0.309-0.924
Differentiation (low vs medium + high)	0.000	0.242	0.242-0.144	0.000	0.326	0.186-0.569
AFP (≤ 200 vs > 200 ng/mL)	0.025	1.914	1.914-1.086	0.042	1.935	1.023-3.662
CASC9 (< 3.305 vs ≥ 3.305)	0.005	2.023	2.023-1.235	0.021	2.024	1.112-3.682

AFP: Alpha fetoprotein; TNM: Tumor, node, metastasis; CASC9: Cancer susceptibility candidate 9.