Influence of bile contamination for patients who undergo pancreaticoduodenectomy after biliary drainage

Table 4 Multivariate analysis for risk factors influencing postoperative pancreatic fistula (Grade B/C) patients who received pancreaticoduodenectomy

Risk factor	Significance (P value)	Odds ratio	95%CI
Male sex	< 0.0001	1.815	1.459-2.266
Age ≥ 70	0.032	1.250	1.018-1.535
BMI (kg/m2) ≥ 25	< 0.0001	2.095	1.610-2.718
Other previous malignancies	0.079	1.253	0.971-1.612
Liver disease	0.119	1.422	0.903-2.200
Preoperative biliary drainage	0.461	1.087	0.869-1.361
Bile contamination	0.026	1.338	1.033-1.729
Soft pancreas	< 0.0001	4.594	3.650-5.824
Operation time (h) ≥ 7	0.0021	1.441	1.143-1.822

BMI: Body mass index; NA: Not available; POPF: Postoperative pancreatic fistula; ISGPF: International Study Group on Pancreatic Fistula; CI: Confidence interval.