Long non-coding RNA HULC as a diagnostic and prognostic marker of pancreatic cancer

Figure 5 Effects of inhibiting the expression of HULC on the Wnt/β-catenin signaling pathway. A: The expression of β-catenin, c-myc, and cyclin D1 proteins in BxPC3 cells after transfection; B: The expression of β-catenin, c-myc, and cyclin D1 proteins in PANC-1 cells after transfection; C: Proliferation of BxPC3 cells with HULC expression inhibited by LiCl; D: Proliferation of PANC-1 cells with HULC expression inhibited by LiCl; E: Apoptosis of BxPC3 and PANC-1 cells with HULC expression inhibited by LiCl; F: Invasion of BxPC3 and PANC-1 cells with HULC expression inhibited by LiCl; G: The expression of β-catenin, c-myc, and cyclin D1 proteins in BxPC3 cells with HULC expression inhibited by LiCl; H: The expression of β-catenin, c-myc, and cyclin D1 proteins in PANC-1 cells with HULC expression inhibited by LiCl; I: Protein band; J: Cell invasion; K: Cell apoptosis. ^aP < 0.05, ^bP < 0.01 for between-group comparisons.