Irisin attenuates intestinal injury, oxidative and endoplasmic reticulum stress in mice with L-arginine-induced acute pancreatitis

Figure 5 Irisin alleviates endoplasmic reticulum stress in experimental acute pancreatitis. Western blot analysis of the expression of glucose-regulated protein 78, protein disulfide isomerase, endoplasmic reticulum oxidoreductase 1-Lα, calnexin, C/EBP homologous protein and perilipin-2 in the intestines. n = 6, mean ± standard error of mean; ^aP < 0.05 vs sham group; ^cP < 0.05 vs vehicle group. AP: Acute pancreatitis; GRP78: Glucose-regulated protein 78; PDI: Protein disulfide isomerase; Ero1-Lα: Endoplasmic reticulum oxidoreductase 1-Lα; CHOP: C/EBP homologous protein; PLIN2: Perilipin-2.