Prognostic value of risk scoring systems for cirrhotic patients with variceal bleeding

Table 3 Discrimination and calibration assessments of all the scoring systems for in-hospital adverse outcomes

Score	AUROC	95%CI	P value	AUROC difference	95%CI	P value	H-L test, P value
In-hospital rebleeding
CTP	0.717	0.648-0.787	< 0.001	Reference			0.134
CRS	0.716	0.638-0.793	< 0.001	0.0016	-0.0851-0.0883	0.9713	0.062
MELD-Na	0.680	0.609-0.752	< 0.001	0.0369	-0.0266-0.1000	0.2547	0.613
MELD	0.661	0.588-0.734	< 0.001	0.0560	-0.0026-0.1150	0.0610	0.386
CANUKA	0.656	0.579-0.732	< 0.001	0.0614	-0.0237- 0.1470	0.1575	0.186
AIMS65	0.642	0.565-0.719	< 0.001	0.0753	0.0120 - 0.1380	0.0196	0.321
GBS	0.617	0.534-0.699	0.003	0.1010	0.0153 - 0.1860	0.0208	0.041
mGBS	0.600	0.518-0.683	0.011	0.1170	0.0314 - 0.2020	0.0074	0.064
In-hospital mortality
CRS	0.883	0.822-0.943	< 0.001	Reference			0.166
CTP	0.878	0.825-0.931	< 0.001	0.0047	-0.0620-0.0714	0.8901	0.566
AIMS65	0.856	0.787-0.925	< 0.001	0.0269	-0.0390-0.0928	0.4232	0.175
MELD-Na	0.856	0.786-0.925	< 0.001	0.0271	-0.0453-0.0995	0.4630	0.636
MELD	0.840	0.767-0.914	< 0.001	0.0423	-0.0360- 0.1210	0.2900	0.472
mGBS	0.734	0.631-0.838	< 0.001	0.1480	0.0552-0.2420	0.0018	0.013
CANUKA	0.728	0.627-0.830	< 0.001	0.1540	0.0675-0.2410	0.0005	0.046
GBS	0.723	0.621-0.826	< 0.001	0.1590	0.0668-0.2520	0.0007	0.004
In-hospital adverse outcomes
CTP	0.784	0.725-0.843	< 0.001	Reference			0.218
CRS	0.775	0.709-0.841	< 0.001	0.0087	-0.0650-0.0824	0.8171	0.002
MELD-Na	0.739	0.675-0.803	< 0.001	0.0446	-0.0136-0.1030	0.1335	0.723
MELD	0.724	0.659-0.789	< 0.001	0.0598	0.0074-0.1120	0.0254	0.464
AIMS65	0.711	0.642-0.780	< 0.001	0.0728	0.0160-0.1300	0.0120	0.101
CANUKA	0.677	0.606-0.748	< 0.001	0.1070	0.0274-0.1860	0.0084	0.023
GBS	0.656	0.582-0.729	< 0.001	0.1280	0.0516-0.2050	0.0010	0.008
mGBS	0.649	0.574-0.723	< 0.001	0.1350	0.0586-0.2120	0.0005	0.024

AUROC: Area under the receiver operating characteristic curve; CI: Confidence interval; H-L: Hosmer-Lemeshow; CTP: Child-Turcotte-Pugh score; MELD: Model for end-stage liver disease; CRS: Clinical Rockall score; GBS: Glasgow-Blatchford score; mGBS: Modified Glasgow-Blatchford score; AIMS65: AIMS65 score; CANUKA: Canada-United Kingdom-Australia score.