Knockdown of lncRNAXLOC_001659 inhibits proliferation and invasion of esophageal squamous cell carcinoma cells

Figure 4 PIK3CA is the target gene of miR-490-5p. A: Bioinformatics analysis demonstrated the binding region between miR-490-5p and PIK3CA; B: Relative luciferase activities of the EC9706 and EC-1 cells co-transfected with PIK3CA-WT or PIK3CA-Mut luciferase reporter vector and miR-NC or MiR-490-5p mimics. ^bP < 0.01; C: MiR-490-5p overexpression inhibited the PIK3CA protein expression in the EC9706 and EC-1 cells.