Knockdown of lncRNAXLOC_001659 inhibits proliferation and invasion of esophageal squamous cell carcinoma cells

Figure 3 MiR-490-5p overexpression and knockdown of lncRNAXLOC_001659 inhibit the proliferation and invasion of esophageal squamous cell carcinoma cells. A: RT-qPCR showed significant more miR-490-5p expression in the EC9706 and EC-1 cells transfected with miR-490-5p mimics than in the corresponding miR-NC groups. ^aP < 0.05 and ^bP < 0.01; B: Colony formation assay showed the changes in colony formation in the EC9706 and EC-1 cells with knockdown of lncXLOC_001659 and overexpression of miR-490-5p, compared with the corresponding NC groups. ^bP < 0.01; C: Transwell invasion assay showed the changes in the invasive cell count in the EC9706 and EC-1 cells with knockdown of lncXLOC_001659 and overexpression of miR-490-5p, compared with the corresponding NC groups. ^aP < 0.05 and ^bP < 0.01.