MicroRNA signature in patients with hepatocellular carcinoma associated with type 2 diabetes

Table 9 Significant relations among candidate serum microRNAs in hepatocellular carcinoma patients

MiRNA name	miR-16	miR-122-5p	miR-198	miR-199a-3p	miR-221	miR-23b-3p	miR-34a
miR-16		NS	r = 0.587	NS	NS	r = 0.682	r = 0.350
			P = 0.001			P ≤ 0.001	P = 0.003
miR-122-5p	NS		NS	r = 0.519	r = 0.372	r = 0.377	r = 0.421
				P = 0.001	P = 0.003	P ≤ 0.001	P = 0.003
miR-198	r = 0.587	NS		NS	r = 0.365	NS	r = 0.450
	P = 0.001				P = 0.004		P ≤ 0.001
miR-199a-3p	NS	r = 0.519	NS		r = 0.381	r = 0.519	NS
		P = 0.001			P = 0.002	P = 0.001
miR-221	NS	r = 0.372	r = 0.365	r = 0.381		r = 0.415	r = 0.392
		P = 0.003	P = 0.004	P = 0.002		P = 0.008	P ≤ 0.001
miR-23b-3p	r = 0.682	r = 0.377	NS	r = 0.519	r = 0.415		r = 0.429
	P ≤ 0.001	P ≤ 0.001		P = 0.001	P = 0.008		P = 0.005
miR-34a	r = 0.350	r = 0.421	r = 0.450	NS	r = 0.392	r = 0.429
	P = 0.003	P = 0.003	P ≤ 0.001		P ≤ 0.001	P = 0.005

HCC: Hepatocellular carcinoma; miRNA: MicroRNA; NS: Nonsignificant correlation.