MicroRNA signature in patients with hepatocellular carcinoma associated with type 2 diabetes

doi:10.3748/wjg.v25.i42.6322

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 14, 2019; 25(42): 6322-6341
Published online Nov 14, 2019. doi: 10.3748/wjg.v25.i42.6322

Table 7 Significant microRNAs expression as average fold change = (2^-ΔΔCT) in the liver cirrhosis group vs the hepatocellular carcinoma group

MiRNA name	HCC	LC	Fold change	Log₂ fold change	P value
hsa-miR-23b-3p	2.44	0.78	0.32	-1.64	0.001^a
hsa-miR-34a	1.88	0.16	0.09	-3.47	0.001^a
hsa-miR-122-5p	0.34	0.98	0.12	2.87	0.001^a
hsa-miR-198	0.88	0.29	0.33	-4.64	0.001^a
hsa-miR-199a-3p	1.18	0.31	0.26	-1.94	0.001^a
hsa-miR-221	1.13	3.31	2.92	1.55	0.001^a

^aP < 0.005 with ± 1.5 log₂ fold expression change. HCC: Hepatocellular carcinoma; LC: Liver cirrhosis; miRNA: MicroRNA.

Citation: Elemeery MN, Mohamed MA, Madkour MA, Shamseya MM, Issa NM, Badr AN, Ghareeb DA, Pan CH. MicroRNA signature in patients with hepatocellular carcinoma associated with type 2 diabetes. World J Gastroenterol 2019; 25(42): 6322-6341
URL: https://www.wjgnet.com/1007-9327/full/v25/i42/6322.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i42.6322