Nucleus tractus solitarius mediates hyperalgesia induced by chronic pancreatitis in rats

doi:10.3748/wjg.v25.i40.6077

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Oct 28, 2019 (publication date) through Feb 7, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 28, 2019; 25(40): 6077-6093
Published online Oct 28, 2019. doi: 10.3748/wjg.v25.i40.6077

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Figure 3 Trinitrobenzene sulfonic acid treatment upregulates the expression of vesicular glutamate transporter 2 within the caudal nucleus tractus solitarius. A: Representative Western blots for VGluT1 and VGluT2 within the caudal nucleus tractus solitarius (NTS) on postoperative days (POD) 7, 14, and 28; B: VGluT1 amount within the caudal NTS showed no changes after trinitrobenzene sulfonic acid (TNBS) treatment; C: VGluT2 amount within the caudal NTS was significantly increased on POD 7, 14, and 28 after TNBS treatment. n = 3 rats per each group, one-way ANOVA, ^aP < 0.05, ^bP < 0.01, TNBS vs sham. TNBS: Trinitrobenzene sulfonic acid; VGluT1: Vesicular glutamate transporter 1; VGluT2: Vesicular glutamate transporter 2.

Citation: Bai Y, Chen YB, Qiu XT, Chen YB, Ma LT, Li YQ, Sun HK, Zhang MM, Zhang T, Chen T, Fan BY, Li H, Li YQ. Nucleus tractus solitarius mediates hyperalgesia induced by chronic pancreatitis in rats. World J Gastroenterol 2019; 25(40): 6077-6093
URL: https://www.wjgnet.com/1007-9327/full/v25/i40/6077.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i40.6077